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Target
85/88 kDa calcium-independent phospholipase A2
Ligand
BDBM50371970
Substrate
n/a
Meas. Tech.
ChEMBL_1911002 (CHEMBL4413448)
IC50
160±n/a nM
Citation
 Mouchlis, VD; Armando, A; Dennis, EA Substrate-Specific Inhibition Constants for Phospholipase A J Med Chem 62:1999-2007 (2019) [PubMed]  Article 
Target
Name:
85/88 kDa calcium-independent phospholipase A2
Synonyms:
Calcium-independent phospholipase A2 | PLA2G6 | PLPL9_HUMAN | PLPLA9
Type:
PROTEIN
Mol. Mass.:
89913.62
Organism:
Homo sapiens (Human)
Description:
ChEMBL_156048
Residue:
806
Sequence:
MQFFGRLVNTFSGVTNLFSNPFRVKEVAVADYTSSDRVREEGQLILFQNTPNRTWDCVLVNPRNSQSGFRLFQLELEADALVNFHQYSSQLLPFYESSPQVLHTEVLQHLTDLIRNHPSWSVAHLAVELGIRECFHHSRIISCANCAENEEGCTPLHLACRKGDGEILVELVQYCHTQMDVTDYKGETVFHYAVQGDNSQVLQLLGRNAVAGLNQVNNQGLTPLHLACQLGKQEMVRVLLLCNARCNIMGPNGYPIHSAMKFSQKGCAEMIISMDSSQIHSKDPRYGASPLHWAKNAEMARMLLKRGCNVNSTSSAGNTALHVAVMRNRFDCAIVLLTHGANADARGEHGNTPLHLAMSKDNVEMIKALIVFGAEVDTPNDFGETPTFLASKIGRLVTRKAILTLLRTVGAEYCFPPIHGVPAEQGSAAPHHPFSLERAQPPPISLNNLELQDLMHISRARKPAFILGSMRDEKRTHDHLLCLDGGGVKGLIIIQLLIAIEKASGVATKDLFDWVAGTSTGGILALAILHSKSMAYMRGMYFRMKDEVFRGSRPYESGPLEEFLKREFGEHTKMTDVRKPKVMLTGTLSDRQPAELHLFRNYDAPETVREPRFNQNVNLRPPAQPSDQLVWRAARSSGAAPTYFRPNGRFLDGGLLANNPTLDAMTEIHEYNQDLIRKGQANKVKKLSIVVSLGTGRSPQVPVTCVDVFRPSNPWELAKTVFGAKELGKMVVDCCTDPDGRAVDRARAWCEMVGIQYFRLNPQLGTDIMLDEVSDTVLVNALWETEVYIYEHREEFQKLIQLLLSP
  
Inhibitor
Name:
BDBM50371970
Synonyms:
CHEMBL89506
Type:
Small organic molecule
Emp. Form.:
C11H19F3OS
Mol. Mass.:
256.328
SMILES:
CCCCCCCCSCC(=O)C(F)(F)F
Structure:
Search PDB for entries with ligand similarity: