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Target
Carboxypeptidase A2
Ligand
BDBM50530232
Substrate
n/a
Meas. Tech.
ChEMBL_1911513 (CHEMBL4413959)
Ki
14±n/a nM
Citation
 Covaleda, G; Gallego, P; Vendrell, J; Georgiadis, D; Lorenzo, J; Dive, V; Aviles, FX; Reverter, D; Devel, L Synthesis and Structural/Functional Characterization of Selective M14 Metallocarboxypeptidase Inhibitors Based on Phosphinic Pseudopeptide Scaffold: Implications on the Design of Specific Optical Probes. J Med Chem 62:1917-1931 (2019) [PubMed]  Article 
Target
Name:
Carboxypeptidase A2
Synonyms:
3.4.17.15 | CBPA2_HUMAN | CPA2 | Carboxypeptidase A2
Type:
PROTEIN
Mol. Mass.:
47025.80
Organism:
Homo sapiens
Description:
ChEMBL_10194
Residue:
419
Sequence:
MAMRLILFFGALFGHIYCLETFVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPTTPGETAHVRVPFVNVQAVKVFLESQGIAYSIMIEDVQVLLDKENEEMLFNRRRERSGNFNFGAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGDKPAIWLDAGIHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRKTRSKVSGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSHGKVKAFITLHSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQSLRSLHGTKYKVGPICSVIYQASGGSIDWSYDYGIKYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHVRDHPY
  
Inhibitor
Name:
BDBM50530232
Synonyms:
CHEMBL4440735
Type:
Small organic molecule
Emp. Form.:
C18H27N2O7P
Mol. Mass.:
414.3899
SMILES:
C[C@H](NC(=O)[C@H](CO)NC(C)=O)P(O)(=O)C[C@@H](CCc1ccccc1)C(O)=O |r|
Structure:
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