Target
Carboxypeptidase A2
Ligand
BDBM50530229
Substrate
n/a
Meas. Tech.
ChEMBL_1911513 (CHEMBL4413959)
Ki
1.000000±n/a nM
Citation
 Covaleda, GGallego, PVendrell, JGeorgiadis, DLorenzo, JDive, VAviles, FXReverter, DDevel, L Synthesis and Structural/Functional Characterization of Selective M14 Metallocarboxypeptidase Inhibitors Based on Phosphinic Pseudopeptide Scaffold: Implications on the Design of Specific Optical Probes. J Med Chem 62:1917-1931 (2019) [PubMed]  Article 
Target
Name:
Carboxypeptidase A2
Synonyms:
3.4.17.15 | CBPA2_HUMAN | CPA2 | Carboxypeptidase A2
Type:
PROTEIN
Mol. Mass.:
47025.80
Organism:
Homo sapiens
Description:
ChEMBL_10194
Residue:
419
Sequence:
MAMRLILFFGALFGHIYCLETFVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPTTPGETAHVRVPFVNVQAVKVFLESQGIAYSIMIEDVQVLLDKENEEMLFNRRRERSGNFNFGAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGDKPAIWLDAGIHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRKTRSKVSGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSHGKVKAFITLHSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQSLRSLHGTKYKVGPICSVIYQASGGSIDWSYDYGIKYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHVRDHPY
  
Inhibitor
Name:
BDBM50530229
Synonyms:
CHEMBL4460840
Type:
Small organic molecule
Emp. Form.:
C26H35N2O6P
Mol. Mass.:
502.5397
SMILES:
CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](Cc1ccccc1)P(O)(=O)C[C@@H](Cc1ccccc1)C(O)=O |r|
Structure:
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