Reaction Details Report a problem with these data
Target
Integrase
Ligand
BDBM50085426
Substrate
n/a
Meas. Tech.
ChEBML_90573
IC50
12000±n/a nM
Citation
 Singh, SB; Felock, P; Hazuda, DJ Chemical and enzymatic modifications of integric acid and HIV-1 integrase inhibitory activity. Bioorg Med Chem Lett 10:235-8 (2000) [PubMed]  Article 
Target
Name:
Integrase
Synonyms:
Human immunodeficiency virus type 1 integrase
Type:
PROTEIN
Mol. Mass.:
32231.48
Organism:
Human immunodeficiency virus 1
Description:
ChEMBL_90865
Residue:
288
Sequence:
FLDGIDKAQDEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTIHTDNGSNFTSTTVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAVFIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRDPLWKGPAKLLWKGEGAVVIQDNSDIKVVPRRKVKIIRDYGKQMAGDDCVASRQDED
  
Inhibitor
Name:
BDBM50085426
Synonyms:
(E)-2,4-Dimethyl-oct-2-enoic acid | CHEMBL421139
Type:
Small organic molecule
Emp. Form.:
C10H18O2
Mol. Mass.:
170.2487
SMILES:
CCCCC(C)\C=C(/C)C(O)=O
Structure:
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