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Target
Fructose-bisphosphate aldolase class 2
Ligand
BDBM75654
Substrate
n/a
Meas. Tech.
ChEMBL_1921621 (CHEMBL4424466)
Ki
880±n/a nM
Citation
 Xiao, S; Wei, L; Hong, Z; Rao, L; Ren, Y; Wan, J; Feng, L Design, synthesis and algicides activities of thiourea derivatives as the novel scaffold aldolase inhibitors. Bioorg Med Chem 27:805-812 (2019) [PubMed]  Article 
Target
Name:
Fructose-bisphosphate aldolase class 2
Synonyms:
4.1.2.13 | ALF2_SYNY3 | FBP aldolase | FBPA | Fructose-1,6-bisphosphate aldolase | Fructose-bisphosphate aldolase class 2 | Fructose-bisphosphate aldolase class II | fbaA | fda | fda
Type:
PROTEIN
Mol. Mass.:
38964.97
Organism:
Synechocystis sp. (strain PCC 6803 / Kazusa)
Description:
ChEMBL_119070
Residue:
359
Sequence:
MALVPMRLLLDHAAENGYGIPAFNVNNMEQIISIMQAADETDSPVILQASRGARSYAGENFLRHLVLGAVETYPHIPIAMHQDHGNSPATCYSAIRNGFTSVMMDGSLEADAKTPASFEYNVNVTAEVVKVAHSVGASVEGELGCLGSLETGQGEAEDGHGFEGKLDHSQLLTDPEEAVEFVNKTQVDALAVAIGTSHGAYKFTRKPTGEVLAISRIEEIHRLLPNTHLVMHGSSSVPQEWIDMINEFGGAIPETYGVPVEEIQKGIKSGVRKVNIDTDNRLAITAAFREAAAKDPKNFDPRHFLKPSIKYMKQVCADRYQQFWTAGNASKIKQLTLDDYAAKYAKGELTATSRTSVAV
  
Inhibitor
Name:
BDBM75654
Synonyms:
4-Fluoro-N-[N'-(2-hydroxy-benzoyl)-hydrazinocarbothioyl]-benzamide | 4-fluoranyl-N-[[(2-hydroxyphenyl)carbonylamino]carbamothioyl]benzamide | 4-fluoro-N-[(salicyloylamino)thiocarbamoyl]benzamide | 4-fluoro-N-[[(2-hydroxybenzoyl)amino]carbamothioyl]benzamide | 4-fluoro-N-[[[(2-hydroxyphenyl)-oxomethyl]hydrazo]-sulfanylidenemethyl]benzamide | MLS001211199 | SMR000516924 | cid_1933071
Type:
Small organic molecule
Emp. Form.:
C15H12FN3O3S
Mol. Mass.:
333.337
SMILES:
Oc1ccccc1C(=O)NNC(=S)NC(=O)c1ccc(F)cc1
Structure:
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