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Target
Gonadotropin-releasing hormone receptor
Ligand
BDBM50090721
Substrate
n/a
Meas. Tech.
ChEMBL_71754 (CHEMBL680276)
Ki
500±n/a nM
Citation
 Yahalom, D; Rahimipour, S; Koch, Y; Ben-Aroya, N; Fridkin, M Structure-activity studies of reduced-size gonadotropin-releasing hormone agonists derived from the sequence of an endothelin antagonist. J Med Chem 43:2824-30 (2000) [PubMed]  Article 
Target
Name:
Gonadotropin-releasing hormone receptor
Synonyms:
GNRHR_RAT | GnRH receptor | GnRH-R | Gnrhr
Type:
PROTEIN
Mol. Mass.:
37767.60
Organism:
Rattus norvegicus
Description:
ChEMBL_1335047
Residue:
327
Sequence:
MANNASLEQDQNHCSAINNSIPLTQGKLPTLTLSGKIRVTVTFFLFLLSTAFNASFLVKLQRWTQKRKKGKKLSRMKVLLKHLTLANLLETLIVMPLDGMWNITVQWYAGEFLCKVLSYLKLFSMYAPAFMMVVISLDRSLAVTQPLAVQSKSKLERSMTSLAWILSIVFAGPQLYIFRMIYLADGSGPAVFSQCVTHCSFPQWWHEAFYNFFTFSCLFIIPLLIMLICNAKIIFALTRVLHQDPRKLQLNQSKNNIPRARLRTLKMTVAFGTSFVICWTPYYVLGIWYWFDPEMLNRVSEPVNHFFFLFAFLNPCFDPLIYGYFSL
  
Inhibitor
Name:
BDBM50090721
Synonyms:
2-{2-[2-[2-[2-(2-Amino-3-methyl-pentanoylamino)-3-methyl-pentanoylamino]-3-(1H-indol-3-yl)-propionylamino]-3-(1H-imidazol-4-yl)-propionylamino]-4-methyl-pentanoylamino}-succinic acid | CHEMBL432052
Type:
Small organic molecule
Emp. Form.:
C39H57N9O9
Mol. Mass.:
795.9248
SMILES:
CCC(C)C(N)C(=O)NC(C(C)CC)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)N[C@H](Cc1cnc[nH]1)C(=O)NC(CC(C)C)C(=O)NC(CC(O)=O)C(O)=O
Structure:
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