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Target
Amine oxidase [flavin-containing] B
Ligand
BDBM50536258
Substrate
n/a
Meas. Tech.
ChEMBL_1933261 (CHEMBL4478913)
IC50
155500±n/a nM
Citation
 Di Pietro, O; Alencar, N; Esteban, G; Viayna, E; Sza?aj, N; Vázquez, J; Juárez-Jiménez, J; Sola, I; Pérez, B; Solé, M; Unzeta, M; Muñoz-Torrero, D; Luque, FJ Design, synthesis and biological evaluation of N-methyl-N-[(1,2,3-triazol-4-yl)alkyl]propargylamines as novel monoamine oxidase B inhibitors. Bioorg Med Chem 24:4835-4854 (2016) [PubMed]  Article 
Target
Name:
Amine oxidase [flavin-containing] B
Synonyms:
AOFB_HUMAN | MAO-B | MAOB | Monoamine oxidase type B | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAOB)
Type:
Protein
Mol. Mass.:
58768.76
Organism:
Homo sapiens (Human)
Description:
P27338
Residue:
520
Sequence:
MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQTRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEERLKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDRIYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTTFLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV
  
Inhibitor
Name:
BDBM50536258
Synonyms:
CHEMBL4555401
Type:
Small organic molecule
Emp. Form.:
C18H24N4
Mol. Mass.:
296.41
SMILES:
CCCCc1c(CCN(C)CC#C)nnn1-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: