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Target
Coiled-coil domain-containing protein 6
Ligand
BDBM50538507
Substrate
n/a
Meas. Tech.
ChEMBL_1973009 (CHEMBL4605827)
IC50
95±n/a nM
Citation
 Mathison, CJN; Chianelli, D; Rucker, PV; Nelson, J; Roland, J; Huang, Z; Yang, Y; Jiang, J; Xie, YF; Epple, R; Bursulaya, B; Lee, C; Gao, MY; Shaffer, J; Briones, S; Sarkisova, Y; Galkin, A; Li, L; Li, N; Li, C; Hua, S; Kasibhatla, S; Kinyamu-Akunda, J; Kikkawa, R; Molteni, V; Tellew, JE Efficacy and Tolerability of Pyrazolo[1,5- ACS Med Chem Lett 11:558-565 (2020) [PubMed]  Article 
Target
Name:
Coiled-coil domain-containing protein 6
Synonyms:
CCDC6 | CCDC6_HUMAN | Coiled-coil domain-containing protein 6 | D10S170 | Papillary thyroid carcinoma-encoded protein | Protein H4 | TST1
Type:
PROTEIN
Mol. Mass.:
53294.85
Organism:
Homo sapiens (Human)
Description:
ChEMBL_109661
Residue:
474
Sequence:
MADSASESDTDGAGGNSSSSAAMQSSCSSTSGGGGGGGGGGGGGKSGGIVISPFRLEELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNTLFKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEFQVNKLMKKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRILQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKMAQYLEEERHMREENLRLQRKLQREMERREALCRQLSESESSLEMDDERYFNEMSAQGLRPRTVSSPIPYTPSPSSSRPISPGLSYASHTVGFTPPTSLTRAGMSYYNSPGLHVQHMGTSHGITRPSPRRSNSPDKFKRPTPPPSPNTQTPVQPPPPPPPPPMQPTVPSAATSQPTPSQHSAHPSSQP
  
Inhibitor
Name:
BDBM50538507
Synonyms:
CHEMBL4640601
Type:
Small organic molecule
Emp. Form.:
C26H29N5O3
Mol. Mass.:
459.5402
SMILES:
COc1ccc(cc1OC)-c1cnn2c(N)c(-c3ccccc3)c(OC3CCN(C)CC3)nc12
Structure:
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