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Target
CAAX prenyl protease 2
Ligand
BDBM50096861
Substrate
n/a
Meas. Tech.
ChEMBL_194934 (CHEMBL879065)
IC50
7000±n/a nM
Citation
 Schlitzer, M; Winter-Vann, A; Casey, PJ Non-peptidic, non-prenylic inhibitors of the prenyl protein-specific protease Rce1. Bioorg Med Chem Lett 11:425-7 (2001) [PubMed]  Article 
Target
Name:
CAAX prenyl protease 2
Synonyms:
CAAX prenyl protease 2 | FACE-2 | FACE2 | FACE2_HUMAN | Farnesylated proteins-converting enzyme 2 | Prenyl protein specific protease | Prenyl protein-specific endoprotease 2 | RCE1 | RCE1 homolog | RCE1A | RCE1B | hRCE1
Type:
PROTEIN
Mol. Mass.:
35839.94
Organism:
Homo sapiens (Human)
Description:
ChEMBL_194935
Residue:
329
Sequence:
MAALGGDGLRLLSVSRPERPPESAALGGLGPGLCCWVSVFSCLSLACSYVGSLYVWKSELPRDHPAVIKRRFTSVLVVSSLSPLCVLLWRELTGIQPGTSLLTLMGFRLEGIFPAALLPLLLTMILFLGPLMQLSMDCPCDLADGLKVVLAPRSWARCLTDMRWLRNQVIAPLTEELVFRACMLPMLAPCMGLGPAVFTCPLFFGVAHFHHIIEQLRFRQSSVGNIFLSAAFQFSYTAVFGAYTAFLFIRTGHLIGPVLCHSFCNYMGFPAVCAALEHPQRRPLLAGYALGVGLFLLLLQPLTDPKLYGSLPLCVLLERAGDSEAPLCS
  
Inhibitor
Name:
BDBM50096861
Synonyms:
CHEMBL440905 | Heptadecanoic acid {[3-(2,3-dimethyl-phenylsulfamoyl)-phenylcarbamoyl]-methyl}-amide
Type:
Small organic molecule
Emp. Form.:
C33H51N3O4S
Mol. Mass.:
585.841
SMILES:
CCCCCCCCCCCCCCCCC(=O)NCC(=O)Nc1cccc(c1)S(=O)(=O)Nc1cccc(C)c1C
Structure:
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