Reaction Details Report a problem with these data
Target
CAAX prenyl protease 2
Ligand
BDBM50096862
Substrate
n/a
Meas. Tech.
ChEBML_194934
IC50
14000±n/a nM
Citation
 Schlitzer, M; Winter-Vann, A; Casey, PJ Non-peptidic, non-prenylic inhibitors of the prenyl protein-specific protease Rce1. Bioorg Med Chem Lett 11:425-7 (2001) [PubMed]  Article 
Target
Name:
CAAX prenyl protease 2
Synonyms:
CAAX prenyl protease 2 | FACE-2 | FACE2 | FACE2_HUMAN | Farnesylated proteins-converting enzyme 2 | Prenyl protein specific protease | Prenyl protein-specific endoprotease 2 | RCE1 | RCE1 homolog | RCE1A | RCE1B | hRCE1
Type:
PROTEIN
Mol. Mass.:
35839.94
Organism:
Homo sapiens (Human)
Description:
ChEMBL_194935
Residue:
329
Sequence:
MAALGGDGLRLLSVSRPERPPESAALGGLGPGLCCWVSVFSCLSLACSYVGSLYVWKSELPRDHPAVIKRRFTSVLVVSSLSPLCVLLWRELTGIQPGTSLLTLMGFRLEGIFPAALLPLLLTMILFLGPLMQLSMDCPCDLADGLKVVLAPRSWARCLTDMRWLRNQVIAPLTEELVFRACMLPMLAPCMGLGPAVFTCPLFFGVAHFHHIIEQLRFRQSSVGNIFLSAAFQFSYTAVFGAYTAFLFIRTGHLIGPVLCHSFCNYMGFPAVCAALEHPQRRPLLAGYALGVGLFLLLLQPLTDPKLYGSLPLCVLLERAGDSEAPLCS
  
Inhibitor
Name:
BDBM50096862
Synonyms:
(9Z,12Z)-Octadeca-9,12-dienoic acid {2-[3-(2,3-dimethyl-phenylsulfamoyl)-phenylcarbamoyl]-ethyl}-amide | CHEMBL135744
Type:
Small organic molecule
Emp. Form.:
C35H51N3O4S
Mol. Mass.:
609.862
SMILES:
CCCCC\C=C/C\C=C/CCCCCCCC(=O)NCCC(=O)Nc1cccc(c1)S(=O)(=O)Nc1cccc(C)c1C
Structure:
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