Reaction Details Report a problem with these data
Target
Sigma intracellular receptor 2
Ligand
BDBM50540780
Substrate
n/a
Meas. Tech.
ChEMBL_1982772 (CHEMBL4616034)
Ki
>10000±n/a nM
Citation
 Amata, E; Dichiara, M; Gentile, D; Marrazzo, A; Turnaturi, R; Arena, E; La Mantia, A; Tomasello, BR; Acquaviva, R; Di Giacomo, C; Rescifina, A; Prezzavento, O Sigma Receptor Ligands Carrying a Nitric Oxide Donor Nitrate Moiety: Synthesis, In Silico, and Biological Evaluation. ACS Med Chem Lett 11:889-894 (2020) [PubMed]  Article 
Target
Name:
Sigma intracellular receptor 2
Synonyms:
MAC30 | Meningioma-associated protein 30 | S2R | SGMR2_HUMAN | Sigma-2 receptor | Sigma2 receptor | TMEM97 | Transmembrane protein 97
Type:
Protein
Mol. Mass.:
20857.20
Organism:
Homo sapiens (Human)
Description:
Q5BJF2
Residue:
176
Sequence:
MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK
  
Inhibitor
Name:
BDBM50540780
Synonyms:
CHEMBL4636837
Type:
Small organic molecule
Emp. Form.:
C8H8O3
Mol. Mass.:
152.1473
SMILES:
OCc1ccc(cc1)C(O)=O
Structure:
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