Reaction Details Report a problem with these data
Target
5-hydroxytryptamine receptor 1A
Ligand
BDBM50541140
Substrate
n/a
Meas. Tech.
ChEMBL_1983771 (CHEMBL4617177)
Ki
1.3±n/a nM
Citation
 Perry, CK; Casey, AB; Felsing, DE; Vemula, R; Zaka, M; Herrington, NB; Cui, M; Kellogg, GE; Canal, CE; Booth, RG Synthesis of novel 5-substituted-2-aminotetralin analogs: 5-HT Bioorg Med Chem 28:0 (2020) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 1A
Synonyms:
5-HT-1A | 5-HT1A | 5-hydroxytryptamine receptor 1A (5-HT-1A) | 5HT1A_HUMAN | ADRB2RL1 | ADRBRL1 | Dopamine D2 receptor and serotonin 1a receptor | G-21 | HTR1A | Serotonin receptor 1A
Type:
n/a
Mol. Mass.:
46122.49
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
422
Sequence:
MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ
  
Inhibitor
Name:
BDBM50541140
Synonyms:
CHEMBL4641769
Type:
Small organic molecule
Emp. Form.:
C20H22FN
Mol. Mass.:
295.3938
SMILES:
Fc1ccccc1-c1cccc2CC(CCc12)N1CCCC1
Structure:
Search PDB for entries with ligand similarity: