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Target
D(2) dopamine receptor
Ligand
BDBM50052869
Substrate
n/a
Meas. Tech.
ChEMBL_62883 (CHEMBL673593)
Ki
233±n/a nM
Citation
 Linnanen, T; Brisander, M; Unelius, L; Rosqvist, S; Nordvall, G; Hacksell, U; Johansson, AM Atropisomeric derivatives of 2',6'-disubstituted (R)-11-phenylaporphine: selective serotonin 5-HT(7) receptor antagonists. J Med Chem 44:1337-40 (2001) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2
Type:
Cell-surface receptors
Mol. Mass.:
50647.10
Organism:
Homo sapiens (Human)
Description:
P14416
Residue:
443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50052869
Synonyms:
(R)-6-Methyl-11-phenyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline | 6-Methyl-11-phenyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline | CHEMBL25924
Type:
Small organic molecule
Emp. Form.:
C23H21N
Mol. Mass.:
311.4195
SMILES:
CN1CCc2cccc-3c2[C@H]1Cc1cccc(-c2ccccc2)c-31
Structure:
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