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Target
Glucagon receptor
Ligand
BDBM50098573
Substrate
n/a
Meas. Tech.
ChEMBL_73018 (CHEMBL681697)
IC50
15±n/a nM
Citation
 Ahn, JM; Medeiros, M; Trivedi, D; Hruby, VJ Development of potent truncated glucagon antagonists. J Med Chem 44:1372-9 (2001) [PubMed]  Article 
Target
Name:
Glucagon receptor
Synonyms:
GL-R | GLR_RAT | Gcgr
Type:
PROTEIN
Mol. Mass.:
55053.40
Organism:
Rattus norvegicus
Description:
ChEMBL_1450588
Residue:
485
Sequence:
MLLTQLHCPYLLLLLVVLSCLPKAPSAQVMDFLFEKWKLYSDQCHHNLSLLPPPTELVCNRTFDKYSCWPDTPPNTTANISCPWYLPWYHKVQHRLVFKRCGPDGQWVRGPRGQSWRDASQCQMDDDEIEVQKGVAKMYSSYQVMYTVGYSLSLGALLLALVILLGLRKLHCTRNYIHGNLFASFVLKAGSVLVIDWLLKTRYSQKIGDDLSVSVWLSDGAVAGCRVATVIMQYGIIANYCWLLVEGVYLYSLLSITTFSEKSFFSLYLCIGWGSPLLFVIPWVVVKCLFENVQCWTSNDNMGFWWILRIPVLLAILINFFIFVRIIHLLVAKLRAHQMHYADYKFRLARSTLTLIPLLGVHEVVFAFVTDEHAQGTLRSTKLFFDLFFSSFQGLLVAVLYCFLNKEVQAELLRRWRRWQEGKALQEERMASSHGSHMAPAGTCHGDPCEKLQLMSAGSSSGTGCEPSAKTSLASSLPRLADSPT
  
Inhibitor
Name:
BDBM50098573
Synonyms:
CHEMBL267876 | N-trinitrophenyl-His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-homoArg-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Leu-Met-Asn-Thr ([N-trinitrophenyl-His1, homo-Arg12] Glucagon)
Type:
Small organic molecule
Emp. Form.:
C160H229N49O54S
Mol. Mass.:
3734.891
SMILES:
n/a
Structure:
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