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Target
Neuraminidase
Ligand
BDBM50098744
Substrate
n/a
Meas. Tech.
ChEMBL_144748 (CHEMBL752730)
IC50
32000±n/a nM
Citation
 Wang, GT; Chen, Y; Wang, S; Gentles, R; Sowin, T; Kati, W; Muchmore, S; Giranda, V; Stewart, K; Sham, H; Kempf, D; Laver, WG Design, synthesis, and structural analysis of influenza neuraminidase inhibitors containing pyrrolidine cores. J Med Chem 44:1192-201 (2001) [PubMed]  Article 
Target
Name:
Neuraminidase
Synonyms:
Influenza A Virus Neuraminidase | NA | NRAM_I34A1 | Neuraminidase | Neuraminidase A
Type:
Enzyme
Mol. Mass.:
50124.14
Organism:
Influenza A virus (A/Puerto Rico/8/34/Mount Sinai(H1N1))
Description:
P03468
Residue:
454
Sequence:
MNPNQKIITIGSICLVVGLISLILQIGNIISIWISHSIQTGSQNHTGICNQNIITYKNSTWVKDTTSVILTGNSSLCPIRGWAIYSKDNSIRIGSKGDVFVIREPFISCSHLECRTFFLTQGALLNDKHSNGTVKDRSPYRALMSCPVGEAPSPYNSRFESVAWSASACHDGMGWLTIGISGPDNGAVAVLKYNGIITETIKSWRKKILRTQESECACVNGSCFTIMTDGPSDGLASYKIFKIEKGKVTKSIELNAPNSHYEECSCYPDTGKVMCVCRDNWHGSNRPWVSFDQNLDYQIGYICSGVFGDNPRPEDGTGSCGPVYVDGANGVKGFSYRYGNGVWIGRTKSHSSRHGFEMIWDPNGWTETDSKFSVRQDVVAMTDWSGYSGSFVQHPELTGLDCMRPCFWVELIRGRPKEKTIWTSASSISFCGVNSDTVDWSWPDGAELPFSIDK
  
Inhibitor
Name:
BDBM50098744
Synonyms:
4-Amino-1-dipropylcarbamoyl-pyrrolidine-3-carboxylic acid | CHEMBL280352
Type:
Small organic molecule
Emp. Form.:
C12H23N3O3
Mol. Mass.:
257.3293
SMILES:
CCCN(CCC)C(=O)N1C[C@H](N)[C@@H](C1)C(O)=O
Structure:
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