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Target
D(2) dopamine receptor
Ligand
BDBM50099255
Substrate
n/a
Meas. Tech.
ChEMBL_60052 (CHEMBL671367)
Ki
28±n/a nM
Citation
 Rowley, M; Hallett, DJ; Goodacre, S; Moyes, C; Crawforth, J; Sparey, TJ; Patel, S; Marwood, R; Patel, S; Thomas, S; Hitzel, L; O'Connor, D; Szeto, N; Castro, JL; Hutson, PH; MacLeod, AM 3-(4-Fluoropiperidin-3-yl)-2-phenylindoles as high affinity, selective, and orally bioavailable h5-HT(2A) receptor antagonists. J Med Chem 44:1603-14 (2001) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2
Type:
Cell-surface receptors
Mol. Mass.:
50647.10
Organism:
Homo sapiens (Human)
Description:
P14416
Residue:
443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50099255
Synonyms:
6-Fluoro-2-(4-fluoro-phenyl)-3-piperidin-3-yl-1H-indole | 6-Fluoro-2-(4-fluorophenyl)-3-(piperidin-3-yl)-1H-indole | CHEMBL296512
Type:
Small organic molecule
Emp. Form.:
C19H18F2N2
Mol. Mass.:
312.3564
SMILES:
Fc1ccc(cc1)-c1[nH]c2cc(F)ccc2c1C1CCCNC1
Structure:
Search PDB for entries with ligand similarity: