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Target
Tubulin alpha-1A chain
Ligand
BDBM50101086
Substrate
n/a
Meas. Tech.
ChEBML_211864
IC50
3100±n/a nM
Citation
 Gwaltney, SL; Imade, HM; Li, Q; Gehrke, L; Credo, RB; Warner, RB; Lee, JY; Kovar, P; Frost, D; Ng, SC; Sham, HL Novel sulfonate derivatives: potent antimitotic agents. Bioorg Med Chem Lett 11:1671-3 (2001) [PubMed]  Article 
Target
Name:
Tubulin alpha-1A chain
Synonyms:
TBA1A_PIG | TUBA1A | Tubulin | Tubulin alpha chain | Tubulin alpha-1A chain
Type:
Protein
Mol. Mass.:
50049.25
Organism:
Sus scrofa (Pig)
Description:
P02550
Residue:
451
Sequence:
MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFSVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRAHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYEPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSVEGEGEEEGEEY
  
Inhibitor
Name:
BDBM50101086
Synonyms:
CHEMBL20684 | E-7010 | N-(2-(4-hydroxyphenylamino)pyridin-3-yl)-4-methoxybenzenesulfonamide | N-[2-(4-Hydroxy-phenylamino)-pyridin-3-yl]-4-methoxy-benzenesulfonamide | N-{2-[(4-hydroxyphenyl)amino]pyridin-3-yl}-4-methoxybenzenesulfonamide
Type:
Small organic molecule
Emp. Form.:
C18H17N3O4S
Mol. Mass.:
371.41
SMILES:
COc1ccc(cc1)S(=O)(=O)Nc1cccnc1Nc1ccc(O)cc1
Structure:
Search PDB for entries with ligand similarity: