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Target
Peroxisome proliferator-activated receptor delta
Ligand
BDBM50545802
Substrate
n/a
Meas. Tech.
ChEMBL_1996626 (CHEMBL4630521)
EC50
>30000±n/a nM
Citation
 Schierle, S; Neumann, S; Heitel, P; Willems, S; Kaiser, A; Pollinger, J; Merk, D Design and Structural Optimization of Dual FXR/PPAR? Activators. J Med Chem 63:8369-8379 (2020) [PubMed]  Article 
Target
Name:
Peroxisome proliferator-activated receptor delta
Synonyms:
NR1C2 | NUC1 | NUCI | Nuclear hormone receptor 1 | Nuclear receptor subfamily 1 group C member 2 | PPAR delta | PPAR-beta | PPARB | PPARD | PPARD_HUMAN | Peroxisome proliferator-activated receptor | Peroxisome proliferator-activated receptor beta | Peroxisome proliferator-activated receptor delta
Type:
Enzyme
Mol. Mass.:
49910.45
Organism:
Homo sapiens (Human)
Description:
Q03181
Residue:
441
Sequence:
MEQPQEEAPEVREEEEKEEVAEAEGAPELNGGPQHALPSSSYTDLSRSSSPPSLLDQLQMGCDGASCGSLNMECRVCGDKASGFHYGVHACEGCKGFFRRTIRMKLEYEKCERSCKIQKKNRNKCQYCRFQKCLALGMSHNAIRFGRMPEAEKRKLVAGLTANEGSQYNPQVADLKAFSKHIYNAYLKNFNMTKKKARSILTGKASHTAPFVIHDIETLWQAEKGLVWKQLVNGLPPYKEISVHVFYRCQCTTVETVRELTEFAKSIPSFSSLFLNDQVTLLKYGVHEAIFAMLASIVNKDGLLVANGSGFVTREFLRSLRKPFSDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGDRPGLMNVPRVEAIQDTILRALEFHLQANHPDAQYLFPKLLQKMADLRQLVTEHAQMMQRIKKTETETSLHPLLQEIYKDMY
  
Inhibitor
Name:
BDBM50545802
Synonyms:
CHEMBL4635036
Type:
Small organic molecule
Emp. Form.:
C24H27NO4
Mol. Mass.:
393.4755
SMILES:
CC(C)c1onc(c1COc1ccc(CCCCC(O)=O)cc1)-c1ccccc1
Structure:
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