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Target
Serine protease 1
Ligand
BDBM50106052
Substrate
n/a
Meas. Tech.
ChEBML_213047
IC50
5170±n/a nM
Citation
 Su, T; Wu, Y; Doughan, B; Jia, ZJ; Woolfrey, J; Huang, B; Wong, P; Park, G; Sinha, U; Scarborough, RM; Zhu, BY Design, synthesis, and SAR of amino acid derivatives as factor Xa inhibitors. Bioorg Med Chem Lett 11:2947-50 (2001) [PubMed]  Article 
Target
Name:
Serine protease 1
Synonyms:
Alpha-trypsin chain 1 | Alpha-trypsin chain 2 | Beta-trypsin | Cationic trypsinogen | PRSS1 | Serine protease 1 | TRP1 | TRY1 | TRY1_HUMAN | TRYP1 | Thrombin & trypsin | Trypsin | Trypsin I | Trypsin-1
Type:
Enzyme
Mol. Mass.:
26557.80
Organism:
Homo sapiens (Human)
Description:
P07477
Residue:
247
Sequence:
MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVSAGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTIAANS
  
Inhibitor
Name:
BDBM50106052
Synonyms:
3-Carbamimidoyl-N-[(S)-phenyl-(2'-sulfamoyl-biphenyl-4-ylcarbamoyl)-methyl]-benzamide | CHEMBL100666
Type:
Small organic molecule
Emp. Form.:
C28H25N5O4S
Mol. Mass.:
527.594
SMILES:
NC(=N)c1cccc(c1)C(=O)N[C@H](C(=O)Nc1ccc(cc1)-c1ccccc1S(N)(=O)=O)c1ccccc1
Structure:
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