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Target
Genome polyprotein
Ligand
BDBM24775
Substrate
n/a
Meas. Tech.
ChEBML_160894
IC50
26000±n/a nM
Citation
 Singh, SB; Graham, PL; Reamer, RA; Cordingley, MG Discovery, total synthesis, HRV 3C-protease inhibitory activity, and structure-activity relationships of 2-methoxystypandrone and its analogues. Bioorg Med Chem Lett 11:3143-6 (2001) [PubMed]  Article 
Target
Name:
Genome polyprotein
Synonyms:
Human rhinovirus A protease | Human rhinovirus B 3A protease
Type:
PROTEIN
Mol. Mass.:
44361.04
Organism:
Human rhinovirus B
Description:
ChEMBL_158953
Residue:
401
Sequence:
AFRPCNVNTKIGNAKCCPFVCGKAVTFKDRSTCSTYNLSSSLHHILEEDKRRRQVVDVMSAIFQGPISLDAPPPPAIADLLQSVRTPRVIKYCQIIMGHPAECQVERDLNIANSIIAIIANIISIAGIIFVIYKLFCSLQGPYSGEPKPKTKVPERRVVAQGPEEEFGRSILKNNTCVITTGNGKFTGLGIHDRILIIPTHADPGREVQVNGVHTKVLDSYDLYNRDGVKLEITVIQLDRNEKFRDIRKYIPETEDDYPECNLALSANQDEPTIIKVGDVVSYGNILLSGNQTARMLKYNYPTKSGYCGGVLYKIGQILGIHVGGNGRDGFSAMLLRSYFTGQIKVNKHATECGLPDIQTIHTPSKTKLQPSVFYDVFPGSKEPAVLTDNDPRLEVNFKEA
  
Inhibitor
Name:
BDBM24775
Synonyms:
2-methoxy-1,4-dihydronaphthalene-1,4-dione | 2-methoxy-1,4-dihydronaphthalene-1,4-dione (5c) | 2-methoxy-1,4-naphthoquinone, 2 | CHEMBL106562
Type:
Small organic molecule
Emp. Form.:
C11H8O3
Mol. Mass.:
188.1794
SMILES:
COC1=CC(=O)c2ccccc2C1=O |t:2|
Structure:
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