Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50348176
Substrate
n/a
Meas. Tech.
ChEMBL_2028574 (CHEMBL4682732)
Ki
0.441000±n/a nM
Citation
 Abdelrahman, A; Yerande, SG; Namasivayam, V; Klapschinski, TA; Alnouri, MW; El-Tayeb, A; Müller, CE Substituted 4-phenylthiazoles: Development of potent and selective A Eur J Med Chem 186:0 (2020) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50348176
Synonyms:
CHEMBL1562432
Type:
Small organic molecule
Emp. Form.:
C16H14Cl3N5O
Mol. Mass.:
398.674
SMILES:
CC[C@@H]1Cn2c(N1)c1nc(nc1n(C)c2=O)-c1cc(Cl)cc(Cl)c1Cl
Structure:
Search PDB for entries with ligand similarity: