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Target
Neuropeptide Y receptor type 5
Ligand
BDBM50110418
Substrate
n/a
Meas. Tech.
ChEBML_144001
IC50
1000±n/a nM
Citation
 Itani, H; Ito, H; Sakata, Y; Hatakeyama, Y; Oohashi, H; Satoh, Y Novel potent antagonists of human neuropeptide Y Y5 receptors. Part 2: substituted benzo[a]cycloheptene derivatives. Bioorg Med Chem Lett 12:757-61 (2002) [PubMed]  Article 
Target
Name:
Neuropeptide Y receptor type 5
Synonyms:
NPY-Y5 | NPY-Y5 receptor | NPY5-R | NPY5R | NPY5R_HUMAN | NPYR5 | NPYY5 | Neuropeptide Y receptor type 5 | Neuropeptide Y receptor type 5 ( NPY Y5) | Y5 receptor
Type:
Enzyme
Mol. Mass.:
50746.64
Organism:
Homo sapiens (Human)
Description:
Q15761
Residue:
445
Sequence:
MDLELDEYYNKTLATENNTAATRNSDFPVWDDYKSSVDDLQYFLIGLYTFVSLLGFMGNLLILMALMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWMFGKVMCHIMPFLQCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYFLIATVWTLGFAICSPLPVFHSLVELQETFGSALLSSRYLCVESWPSDSYRIAFTISLLLVQYILPLVCLTVSHTSVCRSISCGLSNKENRLEENEMINLTLHPSKKSGPQVKLSGSHKWSYSFIKKHRRRYSKKTACVLPAPERPSQENHSRILPENFGSVRSQLSSSSKFIPGVPTCFEIKPEENSDVHELRVKRSVTRIKKRSRSVFYRLTILILVFAVSWMPLHLFHVVTDFNDNLISNRHFKLVYCICHLLGMMSCCLNPILYGFLNNGIKADLVSLIHCLHM
  
Inhibitor
Name:
BDBM50110418
Synonyms:
CHEMBL167926 | Naphthalene-1-sulfonic acid {1-[2-(2-methoxy-6,7,8,9-tetrahydro-5H-benzocyclohepten-6-ylamino)-ethyl]-piperidin-4-ylmethyl}-amide
Type:
Small organic molecule
Emp. Form.:
C30H39N3O3S
Mol. Mass.:
521.714
SMILES:
COc1ccc2CC(CCCc2c1)NCCN1CCC(CNS(=O)(=O)c2cccc3ccccc23)CC1
Structure:
Search PDB for entries with ligand similarity: