Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50041590
Substrate
n/a
Meas. Tech.
ChEMBL_29891 (CHEMBL641962)
Ki
380±n/a nM
Citation
 Hayallah, AM; Sandoval-Ramírez, J; Reith, U; Schobert, U; Preiss, B; Schumacher, B; Daly, JW; Müller, CE 1,8-disubstituted xanthine derivatives: synthesis of potent A2B-selective adenosine receptor antagonists. J Med Chem 45:1500-10 (2002) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50041590
Synonyms:
6-Phenyl-3-propyl-1,5-dihydro-pyrrolo[3,2-d]pyrimidine-2,4-dione | CHEMBL35415
Type:
Small organic molecule
Emp. Form.:
C15H15N3O2
Mol. Mass.:
269.2985
SMILES:
CCCn1c(=O)[nH]c2cc([nH]c2c1=O)-c1ccccc1
Structure:
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