Reaction Details Report a problem with these data
Target
D(4) dopamine receptor
Ligand
BDBM50363893
Substrate
n/a
Meas. Tech.
ChEMBL_2034393 (CHEMBL4688551)
Ki
37±n/a nM
Citation
 Onyameh, EK; Bricker, BA; Eyunni, SVK; Voshavar, C; Gonela, UM; Ofori, E; Jenkins, A; Ablordeppey, SY A study of the structure-affinity relationship in SYA16263; is a D Bioorg Med Chem 30:0 (2021) [PubMed]  Article 
Target
Name:
D(4) dopamine receptor
Synonyms:
D(2C) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.2 | DOPAMINE D4.4 | DRD4 | DRD4_HUMAN | Dopamine D4 receptor
Type:
Enzyme
Mol. Mass.:
48373.19
Organism:
Homo sapiens (Human)
Description:
P21917
Residue:
419
Sequence:
MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVATERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCTASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGRDPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSGPGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPGLPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWTPFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
  
Inhibitor
Name:
BDBM50363893
Synonyms:
CHEMBL1946124
Type:
Small organic molecule
Emp. Form.:
C22H24ClFN2O
Mol. Mass.:
386.89
SMILES:
Fc1ccc2C(=O)C(CCN3CCCN(CC3)c3ccc(Cl)cc3)Cc2c1
Structure:
Search PDB for entries with ligand similarity: