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Target
Tryptase beta-2
Ligand
BDBM50112068
Substrate
n/a
Meas. Tech.
ChEBML_210836
Ki
13700±n/a nM
Citation
 Schaschke, N; Dominik, A; Matschiner, G; Sommerhoff, CP Bivalent inhibition of beta-tryptase: distance scan of neighboring subunits by dibasic inhibitors. Bioorg Med Chem Lett 12:985-8 (2002) [PubMed]  Article 
Target
Name:
Tryptase beta-2
Synonyms:
TPS2 | TPSB2 | TRYB2_HUMAN | Tryptase | Tryptase II | Tryptase beta-1 | Tryptase-2
Type:
PROTEIN
Mol. Mass.:
30518.79
Organism:
Homo sapiens (Human)
Description:
ChEMBL_210702
Residue:
275
Sequence:
MLNLLLLALPVLASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVPKKP
  
Inhibitor
Name:
BDBM50112068
Synonyms:
(R)-2-Acetylamino-3-(3-aminomethyl-phenyl)-propionic acid methyl ester | CHEMBL368533
Type:
Small organic molecule
Emp. Form.:
C13H18N2O3
Mol. Mass.:
250.2936
SMILES:
COC(=O)[C@@H](Cc1cccc(CN)c1)NC(C)=O
Structure:
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