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Target
C-X-C chemokine receptor type 2
Ligand
BDBM50113636
Substrate
n/a
Meas. Tech.
ChEMBL_44676 (CHEMBL656549)
IC50
1200±n/a nM
Citation
 Cutshall, NS; Kucera, KA; Ursino, R; Latham, J; Ihle, NC Nicotinanilides as inhibitors of neutrophil chemotaxis. Bioorg Med Chem Lett 12:1517-20 (2002) [PubMed]  Article 
Target
Name:
C-X-C chemokine receptor type 2
Synonyms:
C-X-C chemokine receptor type 2 (CXCR-2) | C-X-C chemokine receptor type 2 (CXCR2) | CD_antigen=CD182 | CDw128b | CXCR-2 | CXCR2 | CXCR2_HUMAN | Chemokine receptor type 2 (CXCR2) | GRO/MGSA receptor | High affinity interleukin-8 receptor B | IL-8 receptor type 2 | IL-8R B | IL8RB | Interleukin-8 receptor B
Type:
Protein
Mol. Mass.:
40767.88
Organism:
Homo sapiens (Human)
Description:
P25025
Residue:
360
Sequence:
MEDFNMESDSFEDFWKGEDLSNYSYSSTLPPFLLDAAPCEPESLEINKYFVVIIYALVFLLSLLGNSLVMLVILYSRVGRSVTDVYLLNLALADLLFALTLPIWAASKVNGWIFGTFLCKVVSLLKEVNFYSGILLLACISVDRYLAIVHATRTLTQKRYLVKFICLSIWGLSLLLALPVLLFRRTVYSSNVSPACYEDMGNNTANWRMLLRILPQSFGFIVPLLIMLFCYGFTLRTLFKAHMGQKHRAMRVIFAVVLIFLLCWLPYNLVLLADTLMRTQVIQETCERRNHIDRALDATEILGILHSCLNPLIYAFIGQKFRHGLLKILAIHGLISKDSLPKDSRPSFVGSSSGHTSTTL
  
Inhibitor
Name:
BDBM50113636
Synonyms:
CHEMBL39835 | [5-(4-Fluoro-phenylcarbamoyl)-pyridin-2-ylsulfanyl]-acetic acid
Type:
Small organic molecule
Emp. Form.:
C14H11FN2O3S
Mol. Mass.:
306.312
SMILES:
OC(=O)CSc1ccc(cn1)C(=O)Nc1ccc(F)cc1
Structure:
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