Reaction Details Report a problem with these data
Target
Macrophage migration inhibitory factor
Ligand
BDBM50113774
Substrate
n/a
Meas. Tech.
ChEMBL_103857 (CHEMBL712975)
IC50
70000±n/a nM
Citation
Dios, A; Mitchell, RA; Aljabari, B; Lubetsky, J; O'Connor, K; Liao, H; Senter, PD; Manogue, KR; Lolis, E; Metz, C; Bucala, R; Callaway, DJ; Al-Abed, Y Inhibition of MIF bioactivity by rational design of pharmacological inhibitors of MIF tautomerase activity. J Med Chem 45:2410-6 (2002) [PubMed] Article
More Info.:
Target
Name:
Macrophage migration inhibitory factor
Synonyms:
GIF | GLIF | Glycosylation-inhibiting factor | L-dopachrome isomerase | L-dopachrome tautomerase | MIF | MIF/CD74 (Macrophage migration inhibitory factor and HLA-DR antigens-associated invariant chain) | MIF_HUMAN | MMIF | Macrophage migration inhibitory factor | Macrophage migration inhibitory factor (MIF) | Phenylpyruvate tautomerase
Type:
Enzyme
Mol. Mass.:
12478.18
Organism:
Homo sapiens (Human)
Description:
P14174
Residue:
115
Sequence:
MPMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA