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Target
Macrophage migration inhibitory factor
Ligand
BDBM50553885
Substrate
n/a
Meas. Tech.
ChEMBL_2047522 (CHEMBL4702221)
Kd
4400±n/a nM
Citation
Xiao, Z; Chen, D; Song, S; van der Vlag, R; van der Wouden, PE; van Merkerk, R; Cool, RH; Hirsch, AKH; Melgert, BN; Quax, WJ; Poelarends, GJ; Dekker, FJ 7-Hydroxycoumarins Are Affinity-Based Fluorescent Probes for Competitive Binding Studies of Macrophage Migration Inhibitory Factor. J Med Chem 63:11920-11933 (2020) [PubMed] Article
More Info.:
Target
Name:
Macrophage migration inhibitory factor
Synonyms:
GIF | GLIF | Glycosylation-inhibiting factor | L-dopachrome isomerase | L-dopachrome tautomerase | MIF | MIF/CD74 (Macrophage migration inhibitory factor and HLA-DR antigens-associated invariant chain) | MIF_HUMAN | MMIF | Macrophage migration inhibitory factor | Macrophage migration inhibitory factor (MIF) | Phenylpyruvate tautomerase
Type:
Enzyme
Mol. Mass.:
12478.18
Organism:
Homo sapiens (Human)
Description:
P14174
Residue:
115
Sequence:
MPMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA