Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50451431
Substrate
n/a
Meas. Tech.
ChEMBL_47134 (CHEMBL653699)
Ki
18±n/a nM
Citation
 Hynes, J; Leftheris, K; Wu, H; Pandit, C; Chen, P; Norris, DJ; Chen, BC; Zhao, R; Kiener, PA; Chen, X; Turk, LA; Patil-Koota, V; Gillooly, KM; Shuster, DJ; McIntyre, KW C-3 Amido-indole cannabinoid receptor modulators. Bioorg Med Chem Lett 12:2399-402 (2002) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50451431
Synonyms:
CHEMBL2112293
Type:
Small organic molecule
Emp. Form.:
C27H38FN3O3
Mol. Mass.:
471.6073
SMILES:
COc1cc(F)cc2c(C(=O)N[C@H]3C4(C)CCC(C4)C3(C)C)c(C)n(CCN3CCOCC3)c12 |THB:11:12:18:15.16|
Structure:
Search PDB for entries with ligand similarity: