Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50116842
Substrate
n/a
Meas. Tech.
ChEMBL_47134 (CHEMBL653699)
Ki
71±n/a nM
Citation
 Hynes, J; Leftheris, K; Wu, H; Pandit, C; Chen, P; Norris, DJ; Chen, BC; Zhao, R; Kiener, PA; Chen, X; Turk, LA; Patil-Koota, V; Gillooly, KM; Shuster, DJ; McIntyre, KW C-3 Amido-indole cannabinoid receptor modulators. Bioorg Med Chem Lett 12:2399-402 (2002) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50116842
Synonyms:
7-Methoxy-1-(2-morpholin-4-yl-ethyl)-1H-indole-3-carboxylic acid ((S)-1-methyl-2-phenyl-ethyl)-amide | CHEMBL77957
Type:
Small organic molecule
Emp. Form.:
C25H31N3O3
Mol. Mass.:
421.5319
SMILES:
COc1cccc2c(cn(CCN3CCOCC3)c12)C(=O)N[C@@H](C)Cc1ccccc1
Structure:
Search PDB for entries with ligand similarity: