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Target
Protein lifeguard 1
Ligand
BDBM50118479
Substrate
n/a
Meas. Tech.
ChEMBL_140550 (CHEMBL747256)
IC50
287000.0±n/a nM
Citation
 Clausen, RP; Bräuner-Osborne, H; Greenwood, JR; Hermit, MB; Stensbøl, TB; Nielsen, B; Krogsgaard-Larsen, P Selective agonists at group II metabotropic glutamate receptors: synthesis, stereochemistry, and molecular pharmacology of (S)- and (R)-2-amino-4-(4-hydroxy[1,2,5]thiadiazol-3-yl)butyric acid. J Med Chem 45:4240-5 (2002) [PubMed]  Article 
Target
Name:
Protein lifeguard 1
Synonyms:
Glutamate [NMDA] receptor associated protein 1 | Grina | LFG1_RAT | Lfg1 | Nmdara1
Type:
PROTEIN
Mol. Mass.:
38593.19
Organism:
Rattus norvegicus
Description:
ChEMBL_140550
Residue:
348
Sequence:
MSHEKSFLVSGDSYPPPNPGYPVGPQAPMPPYVQPPYPGAPYPQAAFQPSPYGQPGYPHGPGPYPQGGYPQGPYPQGGYPQGPYPQSPFPPNPYGQPPPFQDPGSPQHGNYQEEGPPSYYDNQDFPSVNWDKSIRQAFIRKVFLVLTLQLSVTLSTVAIFTFVGEVKGFVRANVWTYYVSYAIFFISLIVLSCCGDFRRKHPWNLVALSILTISLSYMVGMIASFYNTEAVIMAVGITTAVCFTVVIFSMQTRYDFTSCMGVLLVSVVVLFIFAILCIFIRNRILEIVYASLGALLFTCFLAVDTQLLLGNKQLSLSPEEYVFAALNLYTDIINIFLYILTIIGRAKE
  
Inhibitor
Name:
BDBM50118479
Synonyms:
2-Amino-4-(4-hydroxy-[1,2,5]thiadiazol-3-yl)-butyric acid | CHEMBL334842
Type:
Small organic molecule
Emp. Form.:
C6H9N3O3S
Mol. Mass.:
203.219
SMILES:
N[C@H](CCc1ns[nH]c1=O)C(O)=O
Structure:
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