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Target
Kappa-type opioid receptor
Ligand
BDBM50120058
Substrate
n/a
Meas. Tech.
ChEBML_145959
Ki
184±n/a nM
Citation
 Roy, C; Li, T; Krasik, P; Gilbert, MJ; Pelletier, C; Gagnon, D; Robert, E; Ducharme, J; Storer, R; Lavallée, JF Synthesis and structure--activity relationship of novel aminotetralin derivatives with high micro selective opioid affinity. Bioorg Med Chem Lett 12:3141-3 (2002) [PubMed]  Article 
Target
Name:
Kappa-type opioid receptor
Synonyms:
K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42648.76
Organism:
Homo sapiens (Human)
Description:
P41145
Residue:
380
Sequence:
MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRVRNTVQDPAYLRDIDGMNKPV
  
Inhibitor
Name:
BDBM50120058
Synonyms:
7-Amino-6-methoxy-8,8-dimethyl-5,6,7,8-tetrahydro-naphthalen-2-ol | CHEMBL106432
Type:
Small organic molecule
Emp. Form.:
C13H19NO2
Mol. Mass.:
221.2955
SMILES:
CO[C@@H]1Cc2ccc(O)cc2C(C)(C)[C@@H]1N
Structure:
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