Reaction Details Report a problem with these data
Target
Carboxypeptidase A1
Ligand
BDBM50121275
Substrate
n/a
Meas. Tech.
ChEMBL_45618 (CHEMBL655429)
Ki
180000±n/a nM
Citation
 Park, JD; Kim, DH; Kim, SJ; Woo, JR; Ryu, SE Sulfamide-based inhibitors for carboxypeptidase A. Novel type transition state analogue inhibitors for zinc proteases. J Med Chem 45:5295-302 (2002) [PubMed]  Article 
Target
Name:
Carboxypeptidase A1
Synonyms:
CBPA1_BOVIN | CPA | CPA1 | Carboxypeptidase A | Carboxypeptidase A (CPA) | Carboxypeptidase A1 precursor
Type:
Enzyme
Mol. Mass.:
47073.90
Organism:
Bos taurus (bovine)
Description:
From Sigma-Aldrich Co.
Residue:
419
Sequence:
MQGLLILSVLLGAALGKEDFVGHQVLRITAADEAEVQTVKELEDLEHLQLDFWRGPGQPGSPIDVRVPFPSLQAVKVFLEAHGIRYRIMIEDVQSLLDEEQEQMFASQSRARSTNTFNYATYHTLDEIYDFMDLLVAEHPQLVSKLQIGRSYEGRPIYVLKFSTGGSNRPAIWIDLGIHSREWITQATGVWFAKKFTEDYGQDPSFTAILDSMDIFLEIVTNPDGFAFTHSQNRLWRKTRSVTSSSLCVGVDANRNWDAGFGKAGASSSPCSETYHGKYANSEVEVKSIVDFVKDHGNFKAFLSIHSYSQLLLYPYGYTTQSIPDKTELNQVAKSAVEALKSLYGTSYKYGSIITTIYQASGGSIDWSYNQGIKYSFTFELRDTGRYGFLLPASQIIPTAQETWLGVLTIMEHTLNNLY
  
Inhibitor
Name:
BDBM50121275
Synonyms:
(2S)-2-{[(methylamino)sulfonyl]amino}-3-phenylpropanoic acid | CHEMBL345555
Type:
Small organic molecule
Emp. Form.:
C10H14N2O4S
Mol. Mass.:
258.294
SMILES:
CNS(=O)(=O)N[C@@H](Cc1ccccc1)C(O)=O
Structure:
Search PDB for entries with ligand similarity: