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Target
Sigma non-opioid intracellular receptor 1
Ligand
BDBM50562175
Substrate
n/a
Meas. Tech.
ChEMBL_2077639 (CHEMBL4733430)
Ki
>1000±n/a nM
Citation
 Xie, XY; Li, YY; Ma, WH; Chen, AF; Sun, YT; Lee, JY; Riad, A; Xu, DH; Mach, RH; Huang, YS Synthesis, binding, and functional properties of tetrahydroisoquinolino-2-alkyl phenones as selective ? Eur J Med Chem 209:0 (2021) [PubMed]  Article 
Target
Name:
Sigma non-opioid intracellular receptor 1
Synonyms:
OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein
Type:
Protein
Mol. Mass.:
25307.17
Organism:
Cavia porcellus (Guinea pig)
Description:
Q60492
Residue:
223
Sequence:
MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSKLIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRYWAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
  
Inhibitor
Name:
BDBM50562175
Synonyms:
CHEMBL4749663
Type:
Small organic molecule
Emp. Form.:
C26H35NO8
Mol. Mass.:
489.558
SMILES:
COc1cc2CCN(CCC(=O)c3c(C)c(OC)c(OC)c(OC)c3OC)Cc2c(OC)c1OC
Structure:
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