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Target
Delta-type opioid receptor
Ligand
BDBM50127355
Substrate
n/a
Meas. Tech.
ChEBML_147340
Ki
>1000±n/a nM
Citation
 Pagé, D; Nguyen, N; Bernard, S; Coupal, M; Gosselin, M; Lepage, J; Adam, L; Brown, W New scaffolds in the development of mu opioid-receptor ligands. Bioorg Med Chem Lett 13:1585-9 (2003) [PubMed]  Article 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM50127355
Synonyms:
(R)-2-({[(S)-3-(3-tert-Butyl-ureidomethyl)-3,4-dihydro-1H-isoquinoline-2-carbothioyl]-amino}-methyl)-pyrrolidine-1-carboxylic acid phenylamide | CHEMBL289320
Type:
Small organic molecule
Emp. Form.:
C28H38N6O2S
Mol. Mass.:
522.705
SMILES:
CC(C)(C)NC(=O)NC[C@@H]1Cc2ccccc2CN1C(=S)NC[C@H]1CCCN1C(=O)Nc1ccccc1
Structure:
Search PDB for entries with ligand similarity: