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Target
Ecdysone receptor
Ligand
BDBM50128311
Substrate
n/a
Meas. Tech.
ChEBML_65458
EC50
41950±n/a nM
Citation
 Tice, CM; Hormann, RE; Thompson, CS; Friz, JL; Cavanaugh, CK; Saggers, JA Optimization of alpha-acylaminoketone ecdysone agonists for control of gene expression. Bioorg Med Chem Lett 13:1883-6 (2003) [PubMed]  Article 
Target
Name:
Ecdysone receptor
Synonyms:
n/a
Type:
PROTEIN
Mol. Mass.:
57629.46
Organism:
Choristoneura fumiferana
Description:
ChEMBL_65458
Residue:
513
Sequence:
MDLKHEVAYRGVLPGQVKAEPGVHNGQVNGHVRDWMAGGAGANSPSPGAVAQPQPNNGYSSPLSSGSYGPYSPNGKIGREELSPASSINGCSTDGEARRQKKGPAPRQQEELCLVCGDRASGYHYNALTCEGCKGFFRRSVTKNAVYICKFGHACEMDMYMRRKCQECRLKKCLAVGMRPECVVPETQCAMKRKEKKAQKEKDKLPVSTTTVDDHMPPIMQCEPPPPEAARIHEVVPRFLSDKLLETNRQKNIPQLTANQQFLIARLIWYQDGYEQPSDEDLKRITQTWQQADDENEESDTPFRQITEMTILTVQLIVEFAKGLPGFAKISQPDQITLLKACSSEVMMLRVARRYDAASDSVLFANNQAYTRDNYRKAGMAYVIEDLLHFCRCMYSMALDNIHYALLTAVVIFSDRPGLEQPQLVEEIQRYYLNTLRIYILNQLSGSARSSVIYGKILSILSELRTLGMQNSNMCISLKLKNRKLPPFLEEIWDVADMSHTQPPPILESPTNL
  
Inhibitor
Name:
BDBM50128311
Synonyms:
CHEMBL54983 | N-[2-(3,5-Dimethyl-phenyl)-1,1-dimethyl-2-oxo-ethyl]-3-methoxy-2-methyl-benzamide
Type:
Small organic molecule
Emp. Form.:
C21H25NO3
Mol. Mass.:
339.4281
SMILES:
COc1cccc(C(=O)NC(C)(C)C(=O)c2cc(C)cc(C)c2)c1C
Structure:
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