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Target
Amine oxidase [flavin-containing] A
Ligand
BDBM50564556
Substrate
n/a
Meas. Tech.
ChEMBL_2088326 (CHEMBL4769589)
IC50
>100000±n/a nM
Citation
 Ko?ak, U; Stra?ek, N; Knez, D; Juki?, M; ?akelj, S; Zahirovi?, A; Pi?lar, A; Brazzolotto, X; Nachon, F; Kos, J; Gobec, S N-alkylpiperidine carbamates as potential anti-Alzheimer's agents. Eur J Med Chem 197:0 (2020) [PubMed]  Article 
Target
Name:
Amine oxidase [flavin-containing] A
Synonyms:
AOFA_HUMAN | Amine oxidase (flavin-containing) A | MAO-A | MAOA | Monoamine oxidase | Monoamine oxidase type A | Monoamine oxidase type A (MAO A) | Monoamine oxidase type A (MAO A) | Monoamine oxidase type A (MAOA)
Type:
Protein
Mol. Mass.:
59689.53
Organism:
Homo sapiens (Human)
Description:
P21397
Residue:
527
Sequence:
MENQEKASIAGHMFDVVVIGGGISGLSAAKLLTEYGVSVLVLEARDRVGGRTYTIRNEHVDYVDVGGAYVGPTQNRILRLSKELGIETYKVNVSERLVQYVKGKTYPFRGAFPPVWNPIAYLDYNNLWRTIDNMGKEIPTDAPWEAQHADKWDKMTMKELIDKICWTKTARRFAYLFVNINVTSEPHEVSALWFLWYVKQCGGTTRIFSVTNGGQERKFVGGSGQVSERIMDLLGDQVKLNHPVTHVDQSSDNIIIETLNHEHYECKYVINAIPPTLTAKIHFRPELPAERNQLIQRLPMGAVIKCMMYYKEAFWKKKDYCGCMIIEDEDAPISITLDDTKPDGSLPAIMGFILARKADRLAKLHKEIRKKKICELYAKVLGSQEALHPVHYEEKNWCEEQYSGGCYTAYFPPGIMTQYGRVIRQPVGRIFFAGTETATKWSGYMEGAVEAGERAAREVLNGLGKVTEKDIWVQEPESKDVPAVEITHTFWERNLPSVSGLLKIIGFSTSVTALGFVLYKYKLLPRS
  
Inhibitor
Name:
BDBM50564556
Synonyms:
CHEMBL4792506
Type:
Small organic molecule
Emp. Form.:
C19H22N2O2
Mol. Mass.:
310.3902
SMILES:
O=C(Nc1ccccc1)OC1CCCN(Cc2ccccc2)C1
Structure:
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