Reaction Details Report a problem with these data
Target
Pyroglutamylated RF-amide peptide receptor
Ligand
BDBM50565194
Substrate
n/a
Meas. Tech.
ChEMBL_2091029 (CHEMBL4772292)
Ki
>5000±n/a nM
Citation
 Nguyen, T; Marusich, J; Li, JX; Zhang, Y Neuropeptide FF and Its Receptors: Therapeutic Applications and Ligand Development. J Med Chem 63:12387-12402 (2020) [PubMed]  Article 
Target
Name:
Pyroglutamylated RF-amide peptide receptor
Synonyms:
GPR103 | Pyroglutamylated RFamide peptide receptor | QRFPR | QRFPR_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49508.46
Organism:
Homo sapiens (Human)
Description:
GPR103 0 HUMAN::Q96P65
Residue:
431
Sequence:
MQALNITPEQFSRLLRDHNLTREQFIALYRLRPLVYTPELPGRAKLALVLTGVLIFALALFGNALVFYVVTRSKAMRTVTNIFICSLALSDLLITFFCIPVTMLQNISDNWLGGAFICKMVPFVQSTAVVTEILTMTCIAVERHQGLVHPFKMKWQYTNRRAFTMLGVVWLVAVIVGSPMWHVQQLEIKYDFLYEKEHICCLEEWTSPVHQKIYTTFILVILFLLPLMVMLILYSKIGYELWIKKRVGDGSVLRTIHGKEMSKIARKKKRAVIMMVTVVALFAVCWAPFHVVHMMIEYSNFEKEYDDVTIKMIFAIVQIIGFSNSICNPIVYAFMNENFKKNVLSAVCYCIVNKTFSPAQRHGNSGITMMRKKAKFSLRENPVEETKGEAFSDGNIEVKLCEQTEEKKKLKRHLALFRSELAENSPLDSGH
  
Inhibitor
Name:
BDBM50565194
Synonyms:
CHEMBL4793841
Type:
Small organic molecule
Emp. Form.:
C10H9Cl2N3
Mol. Mass.:
242.105
SMILES:
NC1=NC=C(CN1)c1ccc(Cl)c(Cl)c1 |c:3,t:1|
Structure:
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