Reaction Details Report a problem with these data
Target
DNA repair protein RAD52 homolog
Ligand
BDBM50565803
Substrate
n/a
Meas. Tech.
ChEMBL_2093901 (CHEMBL4775164)
IC50
<5000±n/a nM
Citation
 Myers, SH; Ortega, JA; Cavalli, A Synthetic Lethality through the Lens of Medicinal Chemistry. J Med Chem 63:14151-14183 (2020) [PubMed]  Article 
Target
Name:
DNA repair protein RAD52 homolog
Synonyms:
DNA repair protein RAD52 homolog | RAD52 | RAD52_HUMAN
Type:
PROTEIN
Mol. Mass.:
46177.71
Organism:
Homo sapiens
Description:
ChEMBL_105690
Residue:
418
Sequence:
MSGTEEAILGGRDSHPAAGGGSVLCFGQCQYTAEEYQAIQKALRQRLGPEYISSRMAGGGQKVCYIEGHRVINLANEMFGYNGWAHSITQQNVDFVDLNNGKFYVGVCAFVRVQLKDGSYHEDVGYGVSEGLKSKALSLEKARKEAVTDGLKRALRSFGNALGNCILDKDYLRSLNKLPRQLPLEVDLTKAKRQDLEPSVEEARYNSCRPNMALGHPQLQQVTSPSRPSHAVIPADQDCSSRSLSSSAVESEATHQRKLRQKQLQQQFRERMEKQQVRVSTPSAEKSEAAPPAPPVTHSTPVTVSEPLLEKDFLAGVTQELIKTLEDNSEKWAVTPDAGDGVVKPSSRADPAQTSDTLALNNQMVTQNRTPHSVCHQKPQAKSGSWDLQTYSADQRTTGNWESHRKSQDMKKRKYDPS
  
Inhibitor
Name:
BDBM50565803
Synonyms:
CHEMBL4777728
Type:
Small organic molecule
Emp. Form.:
C8H9NO2
Mol. Mass.:
151.1626
SMILES:
Cn1cccc1C=CC(O)=O
Structure:
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