Reaction Details Report a problem with these data
Target
Beta-galactosidase
Ligand
BDBM50133505
Substrate
n/a
Meas. Tech.
ChEMBL_37271 (CHEMBL656021)
IC50
3700±n/a nM
Citation
 Ogawa, S; Fujieda, S; Sakata, Y; Ishizaki, M; Hisamatsu, S; Okazaki, K Synthesis and glycosidase inhibitory activity of some N-substituted 6-deoxy-5a-carba-beta-DL- and L-galactopyranosylamines. Bioorg Med Chem Lett 13:3461-3 (2003) [PubMed]  Article 
Target
Name:
Beta-galactosidase
Synonyms:
β-galactosidase | BGAL_BOVIN | Beta-galactosidase/Glucosylceramidase | GLB1
Type:
Protein
Mol. Mass.:
73420.88
Organism:
Bos taurus (Bovine)
Description:
n/a
Residue:
653
Sequence:
MPGVVRLLALLLVPLLLGSARGLHNATQRTFQIDYRRNRFLKDGQPFRYISGSIHYFRVPRFYWKDRLLKMKMAGLNAIQTYVAWNFHELQPGRYNFSGDHDVEHFIQLAHELGLLVILRPGPYICAEWDMGGLPAWLLEKKSIVLRSSDPDYLAAVDKWLGVLLPKMRPLLYKNGGPIITVQVENEYGSYLSCDYDYLRFLQKRFHDHLGEDVLLFTTDGVNERLLQCGALQGLYATVDFSPGTNLTAAFMLQRKFEPTGPLVNSEFYTGWLDHWGQRHSTVSSKAVAFTLHDMLALGANVNMYMFIGGTNFAYWNGANIPYQPQPTSYDYDAPLSEAGDLTEKYFALRDIIQKFAKVPEGPIPPSTPKFAYGKVALNKLKTVEDALNILCPSGPIKSVYPLTFIDVKQYFGFVLYRTMLPEDCSDPTPLSSPLSGVHDRAYVSVNGVAQGILERESVITLNITGKAGATLDLLVENMGRVNYGSSINDFKGLVSNLTLGSKILTNWEIFPLDMEDAVRSHLGTWGGRDRGYHNKARAHSPPTYALPTFYVGNFTIPSGIADLPQDTFIQFPGWTKGQVWINGFNLGRYWPVRGPQMTLFVPQHILVTSTPNTIVVLELEHAPCQDGGPELCTVEFVDKPVFRTVQTHRHAN
  
Inhibitor
Name:
BDBM50133505
Synonyms:
(1R,3R,6S)-4-Methyl-6-octylamino-cyclohexane-1,2,3-triol | CHEMBL117201
Type:
Small organic molecule
Emp. Form.:
C15H31NO3
Mol. Mass.:
273.4115
SMILES:
CCCCCCCCN[C@H]1CC(C)[C@@H](O)C(O)[C@@H]1O
Structure:
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