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Target
Neuropeptide Y receptor type 2
Ligand
BDBM50135650
Substrate
n/a
Meas. Tech.
ChEBML_143843
IC50
>10000±n/a nM
Citation
 Andres, CJ; Antal Zimanyi, I; Deshpande, MS; Iben, LG; Grant-Young, K; Mattson, GK; Zhai, W Differentially functionalized diamines as novel ligands for the NPY2 receptor. Bioorg Med Chem Lett 13:2883-5 (2003) [PubMed]  Article 
Target
Name:
Neuropeptide Y receptor type 2
Synonyms:
NPY-Y2 | NPY-Y2 receptor | NPY2-R | NPY2R | NPY2R_HUMAN | Neuropeptide Y receptor type 2 | Y2 receptor | neuropeptide Y receptor Y2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
42734.65
Organism:
Homo sapiens (Human)
Description:
NPY-Y2 NPY2R HUMAN::P49146
Residue:
381
Sequence:
MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSIILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRIWSKLKNHVSPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSVTFKAKKNLEVRKNSGPNDSFTEATNV
  
Inhibitor
Name:
BDBM50135650
Synonyms:
Benzo[b]thiophene-2-carboxylic acid (2-benzylsulfanyl-phenyl)-(4-dimethylamino-butyl)-amide | CHEMBL420630
Type:
Small organic molecule
Emp. Form.:
C28H30N2OS2
Mol. Mass.:
474.681
SMILES:
CN(C)CCCCN(C(=O)c1cc2ccccc2s1)c1ccccc1SCc1ccccc1
Structure:
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