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Target
D(4) dopamine receptor
Ligand
BDBM50135709
Substrate
n/a
Meas. Tech.
ChEBML_61005
Ki
22±n/a nM
Citation
 Thurkauf, A; Chen, X; Zhang, S; Gao, Y; Kieltyka, A; Wasley, JW; Brodbeck, R; Greenlee, W; Ganguly, A; Zhao, H 1H-Pyrazolo-[3,4-c]cyclophepta[1,2-c]thiophenes: a unique structural class of dopamine D4 selective ligands. Bioorg Med Chem Lett 13:2921-4 (2003) [PubMed]  Article 
Target
Name:
D(4) dopamine receptor
Synonyms:
D(2C) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.2 | DOPAMINE D4.4 | DRD4 | DRD4_HUMAN | Dopamine D4 receptor
Type:
Enzyme
Mol. Mass.:
48373.19
Organism:
Homo sapiens (Human)
Description:
P21917
Residue:
419
Sequence:
MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVATERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCTASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGRDPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSGPGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPGLPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWTPFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
  
Inhibitor
Name:
BDBM50135709
Synonyms:
1-Ethyl-7,9-dimethyl-1,4,5,6-tetrahydro-8-thia-1,2-diaza-cyclopenta[e]azulene | CHEMBL99208
Type:
Small organic molecule
Emp. Form.:
C14H18N2S
Mol. Mass.:
246.371
SMILES:
CCn1ncc2CCCc3c(C)sc(C)c3-c12
Structure:
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