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Target
Integrase
Ligand
BDBM50136322
Substrate
n/a
Meas. Tech.
ChEBML_90554
IC50
5300±n/a nM
Citation
 Lee, JY; Yoon, KJ; Lee, YS Catechol-substituted L-chicoric acid analogues as HIV integrase inhibitors. Bioorg Med Chem Lett 13:4331-4 (2003) [PubMed]  Article 
Target
Name:
Integrase
Synonyms:
Human immunodeficiency virus type 1 integrase
Type:
PROTEIN
Mol. Mass.:
32231.48
Organism:
Human immunodeficiency virus 1
Description:
ChEMBL_90865
Residue:
288
Sequence:
FLDGIDKAQDEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTIHTDNGSNFTSTTVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAVFIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRDPLWKGPAKLLWKGEGAVVIQDNSDIKVVPRRKVKIIRDYGKQMAGDDCVASRQDED
  
Inhibitor
Name:
BDBM50136322
Synonyms:
3,4-Bis-(3,4-dihydroxy-phenyl)-1H-pyrrole-2,5-dicarboxylic acid | CHEMBL342488
Type:
Small organic molecule
Emp. Form.:
C18H13NO8
Mol. Mass.:
371.2977
SMILES:
OC(=O)c1[nH]c(C(O)=O)c(c1-c1ccc(O)c(O)c1)-c1ccc(O)c(O)c1
Structure:
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