Reaction Details Report a problem with these data
Target
Melanocortin receptor 4
Ligand
BDBM50139791
Substrate
n/a
Meas. Tech.
ChEMBL_106343 (CHEMBL713798)
IC50
100±n/a nM
Citation
 Bondensgaard, K; Ankersen, M; Thøgersen, H; Hansen, BS; Wulff, BS; Bywater, RP Recognition of privileged structures by G-protein coupled receptors. J Med Chem 47:888-99 (2004) [PubMed]  Article 
Target
Name:
Melanocortin receptor 4
Synonyms:
MC4-R | MC4R | MC4R_HUMAN | Melanocortin MC4 | Melanocortin receptor 4 (MC-4) | Melanocortin receptor 4 (MC4-R) | Melanocortin receptor 4 (MC4R)
Type:
Enzyme
Mol. Mass.:
36949.50
Organism:
Homo sapiens (Human)
Description:
P32245
Residue:
332
Sequence:
MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY
  
Inhibitor
Name:
BDBM50139791
Synonyms:
CHEMBL353007 | MC4 ligand
Type:
Small organic molecule
Emp. Form.:
C32H35ClN4O4S
Mol. Mass.:
607.163
SMILES:
CS(=O)(=O)N1CC2(CCN(CC2)C(=O)[C@@H](Cc2ccc(Cl)cc2)NC(=O)C2Cc3ccccc3CN2)c2ccccc12
Structure:
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