Reaction Details Report a problem with these data
Target
Fibroblast growth factor 2
Ligand
BDBM50144526
Substrate
n/a
Meas. Tech.
ChEBML_70634
Kd
16000±n/a nM
Citation
 Liu, L; Ping Li, C; Cochran, S; Ferro, V Application of the four-component Ugi condensation for the preparation of sulfated glycoconjugate libraries. Bioorg Med Chem Lett 14:2221-6 (2004) [PubMed]  Article 
Target
Name:
Fibroblast growth factor 2
Synonyms:
Basic fibroblast growth factor | FGF-2 | FGF2 | FGF2_HUMAN | FGFB | Fibroblast growth factor 2 (bFGF) | Fibroblast growth factor receptor 2 (FGF-2) | HBGF-2 | Heparin-binding growth factor 2
Type:
Protein
Mol. Mass.:
30803.89
Organism:
Homo sapiens (Human)
Description:
P09038
Residue:
288
Sequence:
MVGVGGGDVEDVTPRPGGCQISGRGARGCNGIPGAAAWEAALPRRRPRRHPSVNPRSRAAGSPRTRGRRTEERPSGSRLGDRGRGRALPGGRLGGRGRGRAPERVGGRGRGRGTAAPRAAPAARGSRPGPAGTMAAGSITTLPALPEDGGSGAFPPGHFKDPKRLYCKNGGFFLRIHPDGRVDGVREKSDPHIKLQLQAEERGVVSIKGVCANRYLAMKEDGRLLASKCVTDECFFFERLESNNYNTYRSRKYTSWYVALKRTGQYKLGSKTGPGQKAILFLPMSAKS
  
Inhibitor
Name:
BDBM50144526
Synonyms:
CHEMBL3215304 | Sodium sulfated glycoconjugate derivative
Type:
Small organic molecule
Emp. Form.:
C26H33N2Na7O35S7
Mol. Mass.:
1318.916
SMILES:
[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].CO[C@H]1O[C@@H](COCC(=O)N(CC(=O)NCCO[C@H]2O[C@@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@H]2OS([O-])(=O)=O)Cc2ccccc2)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@H]1OS([O-])(=O)=O |r|
Structure:
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