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Target
D(4) dopamine receptor
Ligand
BDBM50147955
Substrate
n/a
Meas. Tech.
ChEMBL_60693 (CHEMBL676503)
Ki
9.3±n/a nM
Citation
 Audouze, K; Nielsen, EŘ; Peters, D New series of morpholine and 1,4-oxazepane derivatives as dopamine D4 receptor ligands: synthesis and 3D-QSAR model. J Med Chem 47:3089-104 (2004) [PubMed]  Article 
Target
Name:
D(4) dopamine receptor
Synonyms:
D(2C) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.2 | DOPAMINE D4.4 | DRD4 | DRD4_HUMAN | Dopamine D4 receptor
Type:
Enzyme
Mol. Mass.:
48373.19
Organism:
Homo sapiens (Human)
Description:
P21917
Residue:
419
Sequence:
MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVATERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCTASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGRDPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSGPGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPGLPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWTPFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
  
Inhibitor
Name:
BDBM50147955
Synonyms:
4-(4-Chloro-benzyl)-2-(5-chloro-2-ethoxy-phenoxymethyl)-[1,4]oxazepane | CHEMBL107691
Type:
Small organic molecule
Emp. Form.:
C21H25Cl2NO3
Mol. Mass.:
410.334
SMILES:
CCOc1ccc(Cl)cc1OCC1CN(Cc2ccc(Cl)cc2)CCCO1
Structure:
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