Reaction Details Report a problem with these data
Target
Platelet glycoprotein 4
Ligand
BDBM50581262
Substrate
n/a
Meas. Tech.
ChEMBL_2150268 (CHEMBL5034730)
IC50
9050±n/a nM
Citation
 Ohm, RG; Mulumba, M; Chingle, RM; Ahsanullah, na; Zhang, J; Chemtob, S; Ong, H; Lubell, WD Diversity-Oriented A J Med Chem 64:9365-9380 (2021) [PubMed]  Article 
Target
Name:
Platelet glycoprotein 4
Synonyms:
Adipocyte membrane protein | CD36_RAT | CD_antigen=CD36 | Cd36 | Fat | Fatty acid translocase | Fatty acid transport protein | GPIIIB | GPIV | Glycoprotein IIIb | PAS IV | PAS-4 | Platelet glycoprotein IV
Type:
PROTEIN
Mol. Mass.:
52740.95
Organism:
Rattus norvegicus
Description:
ChEMBL_858884
Residue:
472
Sequence:
MGCDRNCGLITGAVIGAVLAVFGGILMPVGDLLIEKTIKREVVLEEGTIAFKNWVKTGTTVYRQFWIFDVQNPEEVAKNSSKIKVKQRGPYTYRVRYLAKENITQDPKDSTVSFVQPNGAIFEPSLSVGTENDNFTVLNLAVAAAPHIYTNSFVQGVLNSLIKKSKSSMFQTRSLKELLWGYKDPFLSLVPYPISTTVGVFYPYNNTVDGVYKVFNGKDNISKVAIIDTYKGKRNLSYWESYCDMINGTDAASFPPFVEKSQTLRFFSSDICRSIYAVFESEVNLKGIPVYRFVLPANAFASPLQNPDNHCFCTEKVISNNCTSYGVLDIGKCKEGKPVYISLPHFLHASPDVSEPIEGLNPNEDEHRTYLDVEPITGFTLQFAKRLQVNILVKPARKIEALKNLKRPYIVPILWLNETGTIGDEKAEMFRNQVTGKIKLLGLVEMVLLGVGVVMFVAFMISYCACRSKNGK
  
Inhibitor
Name:
BDBM50581262
Synonyms:
CHEMBL5086116
Type:
Small organic molecule
Emp. Form.:
C52H66N12O7
Mol. Mass.:
971.1566
SMILES:
C[C@H](N)C(=O)NN1C\C=C/CN(CC2CC2)CCCC[C@H](NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](C)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC1=O)C(N)=O |r,c:8|
Structure:
Search PDB for entries with ligand similarity: