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Target
Cannabinoid receptor 2
Ligand
BDBM50582406
Substrate
n/a
Meas. Tech.
ChEMBL_2154508 (CHEMBL5039168)
Ki
0.800000±n/a nM
Citation
 Jiang, S; Iliopoulos-Tsoutsouvas, C; Tong, F; Brust, CA; Keenan, CM; Raghav, JG; Hua, T; Wu, S; Ho, JH; Wu, Y; Grim, TW; Zvonok, N; Thakur, GA; Liu, ZJ; Sharkey, KA; Bohn, LM; Nikas, SP; Makriyannis, A Novel Functionalized Cannabinoid Receptor Probes: Development of Exceptionally Potent Agonists. J Med Chem 64:3870-3884 (2021) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CNR2_MOUSE | Cannabinoid CB2 receptor | Cannabinoid receptor | Cannabinoid receptor 2 | Cnr2 | mCB2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
38220.43
Organism:
MOUSE
Description:
P47936
Residue:
347
Sequence:
MEGCRETEVTNGSNGGLEFNPMKEYMILSSGQQIAVAVLCTLMGLLSALENMAVLYIILSSRRLRRKPSYLFISSLAGADFLASVIFACNFVIFHVFHGVDSNAIFLLKIGSVTMTFTASVGSLLLTAVDRYLCLCYPPTYKALVTRGRALVALCVMWVLSALISYLPLMGWTCCPSPCSELFPLIPNDYLLGWLLFIAILFSGIIYTYGYVLWKAHRHVATLAEHQDRQVPGIARMRLDVRLAKTLGLVLAVLLICWFPALALMGHSLVTTLSDQVKEAFAFCSMLCLVNSMVNPIIYALRSGEIRSAAQHCLIGWKKYLQGLGPEGKEEGPRSSVTETEADVKTT
  
Inhibitor
Name:
BDBM50582406
Synonyms:
CHEMBL5091754
Type:
Small organic molecule
Emp. Form.:
C26H39NO3
Mol. Mass.:
413.5928
SMILES:
[H][C@@]12C[C@H](CO)CC[C@@]1([H])C(C)(C)Oc1cc(cc(O)c21)C(C)(C)CCCCCCC#N |r|
Structure:
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