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Target
N-formyl peptide receptor 2
Ligand
BDBM50582813
Substrate
n/a
Meas. Tech.
ChEMBL_2155733 (CHEMBL5040393)
EC50
8.0±n/a nM
Citation
 Maciuszek, M; Ortega-Gomez, A; Maas, SL; Garrido-Mesa, J; Ferraro, B; Perretti, M; Merritt, A; Nicolaes, GAF; Soehnlein, O; Chapman, TM Design, synthesis, and biological evaluation of novel pyrrolidinone small-molecule Formyl peptide receptor 2 agonists. Eur J Med Chem 226:0 (2021) [PubMed]  Article 
Target
Name:
N-formyl peptide receptor 2
Synonyms:
ALXR, FPRL1, FPR2 | FMLP-related receptor I FMLP-R-I | FPR2 | FPR2_HUMAN | FPRH1 | FPRL1 | Formyl Peptide Receptor-Like 1 | HM63 | LXA4 receptor | LXA4R | Lipoxin A4 receptor | Lipoxin A4 receptor (LXA4) | RFP | hFPRL
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
38968.35
Organism:
Homo sapiens (Human)
Description:
P25090
Residue:
351
Sequence:
METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVTTICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIALDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNFASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPLRVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPMLYVFVGQDFRERLIHSLPTSLERALSEDSAPTNDTAANSASPPAETELQAM
  
Inhibitor
Name:
BDBM50582813
Synonyms:
CHEMBL5093348
Type:
Small organic molecule
Emp. Form.:
C20H23BrN6O2
Mol. Mass.:
459.34
SMILES:
Brc1ccc(NC(=O)NC2CCN(C3CCN(CC3)c3ncccn3)C2=O)cc1
Structure:
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