Reaction Details Report a problem with these data
Target
Melatonin receptor type 1A
Ligand
BDBM50153430
Substrate
n/a
Meas. Tech.
ChEMBL_303582 (CHEMBL828981)
Ki
39±n/a nM
Citation
 Sun, LQ; Takaki, K; Chen, J; Iben, L; Knipe, JO; Pajor, L; Mahle, CD; Ryan, E; Xu, C N-[2-[2-(4-Phenylbutyl)benzofuran-4-yl]cyclopropylmethyl]acetamide: an orally bioavailable melatonin receptor agonist. Bioorg Med Chem Lett 14:5157-60 (2004) [PubMed]  Article 
Target
Name:
Melatonin receptor type 1A
Synonyms:
MTNR1A | MTNR1A protein | MTR1A_HUMAN | Mel-1A-R | Mel1a melatonin receptor | Melatonin 1A | Melatonin receptor | Melatonin receptor 1A | Melatonin receptor type 1 (MT1) | Melatonin receptor type 1A
Type:
Enzyme
Mol. Mass.:
39392.94
Organism:
Homo sapiens (Human)
Description:
P48039
Residue:
350
Sequence:
MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFAQSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTMFVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
  
Inhibitor
Name:
BDBM50153430
Synonyms:
1-Ethyl-3-{(S)-1-[2-(4-phenyl-butyl)-benzofuran-4-yl]-pyrrolidin-3-yl}-urea | CHEMBL359561
Type:
Small organic molecule
Emp. Form.:
C25H31N3O2
Mol. Mass.:
405.5325
SMILES:
CCNC(=O)N[C@H]1CCN(C1)c1cccc2oc(CCCCc3ccccc3)cc12
Structure:
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